The Drone Company Everyone Thought Was Illegal (Now Worth $4B+) | E2265 - This Week in Startups Recap

Podcast: This Week in Startups

Published: 2026-03-20

Guests: Keller Clifton, Raul Vora, Rahul Vohra

What Happened

Zipline, founded in 2011, initially encountered skepticism from investors who questioned the legality and expertise needed for drone operations. Despite this, by 2016, the company had begun delivering blood transfusions to hospitals in Rwanda, overcoming early operational challenges to reliably serve one hospital within nine months.

Zipline's drones have flown over a million miles autonomously, delivering within a 100-mile radius and covering distances up to 300 miles. A University of Pennsylvania study revealed a 51% reduction in maternal mortality in hospitals serviced by Zipline, highlighting the impact of their operations.

In the U.S., Zipline's Platform 2, a hybrid drone system, partners with major brands like Walmart, Chipotle, and Buffalo Wild Wings. With a net promoter score of 95, the service is favored for its accuracy and safety, delivering with dinner plate precision using a droid that descends from the main aircraft.

Zipline's ability to operate in extreme weather and deliver 80-90,000 out of 100,000 SKUs from a Walmart supercenter demonstrates its operational resilience and efficiency. The company serves a diverse customer base, including an 80-year-old who ordered 350 times in a year, showing high adoption among non-tech enthusiasts.

The company recently raised $850 million, achieving an $8 billion valuation, and plans to expand to new metros like Houston and Phoenix. With operations in Dallas growing 15% week over week and expectations to grow by 15x, Zipline is poised to become the largest Part 135 certified operator in the U.S. by year-end.

Raul Vora, founder of Superhuman, shared insights on his entrepreneurial journey, including the acquisition of Superhuman by Grammarly. His first startup, Reportive, was born out of the need for better email contact information and was eventually acquired by LinkedIn for $15 million. Vora emphasized the importance of angel investing and building a product that users love.

Key Insights